Biotin, sometimes called vitamin H, is a water-soluble vitamin. Most people take biotin in high doses without causing actual side effects. Its common side effect is cystic acne breakouts. In addition, pregnant women should not take biotin because of the risk of miscarriage.
Biotin is an element required for gluconeogenesis, and it is also required for fatty acid synthesis and production. Biotin assists the body's metabolic functions, including regulating blood sugar levels and carbohydrate function. It also plays a role in the citric acid cycle and aiding in aerobic respiration. In addition, it can also be found in the amino acid leucine.
The most common side effect of biotin is cystic acne breakouts on the jaw and chin. But everyone's experience is different. Life-threatening side effects are rare, and the only documented case is a woman who developed eosinophilic pleuropericardial effusion, a dangerous condition involving the lungs and chest cavity, after taking biotin. She was taking a lot of biotin at the time along with vitamin B5. However, after stopping taking these two vitamins, my health has returned. Whether the disease is caused by biotin or vitamin B5 alone, or the result of a combination of the two, remains unclear.
Normal healthy adults rarely develop biotin deficiency, but people who consume large amounts of avidin or those with skin and hair disorders such as phenylketonuria sometimes experience it. Biotin deficiency usually takes several years to develop because it occurs naturally and can be recycled by the human gut.
Studies have found that about 50% of pregnant women are deficient in biotin. Because they lack an enzyme that tells the body how to use biotin correctly, they have reduced metabolic function. But most doctors do not recommend biotin supplements as a treatment, because experiments in animals have found them to be prone to fetal development abnormalities and miscarriage.
Biotin is often suggested as a supplement to promote hair and nail growth. In addition, it is often used as a weight-loss supplement due to its effect on carbohydrates. The recommended dose is between 3-5000 micrograms per day. Since the side effects of biotin are rare and mild and manageable, it is generally a safe supplement.
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