Liver Protection

A: The effective dose for preventing hangovers is 300‐600mg taken per 3 alcoholic drinks consumed. An alcoholic drink is defined as a single 12oz beer (4.3% alcohol) or 1.5oz of liquor (35% alcohol). This means if you consume 6 shots of rum in a night, the most effective dose ranges from600‐1,200mg.

A: Dihydromyricetin is a flavonoid isolated from Ampelopsis grossedentata, which is traditionally used in China. Dihydromyricetin exhibits health-benefiting activities with minimum adverse effects. Dihydromyricetin has been demonstrated to show antioxidative, anti-inflammatory, anticancer, antimicrobial, cell death-mediating, and lipid and glucose metabolism-regulatory activities. Dihydromyricetin may scavenge ROS to protect against oxidative stress or potentiate ROS generation to counteract cancer cells selectively without any effects on normal cells.

A: Dihydromyricetin (DMY), also known as ampeloptin, is a flavonoid extracted from the stems and leaves of the A. grossedentata. It is also widely found in Japanese raisin trees (Hovenia dulcis Thunb.), grapes, bayberry, ginkgo and other plants, and is very high in vine tea, often reaching 30~40%.

A: Building evidence suggests that dihydromyricetin (DHM), a bioactive flavonoid isolated from Hovenia dulcis, provides hepatoprotection by enhancing ethanol metabolism in the liver by maintaining hepatocellular bioenergetics, reductions of oxidative stress, and activating lipid oxidation pathways.

A: DHM is not approved for any use or disease in humans in the United States but is available in nutrition centers and on the internet. The typical dose in 300 to 1000 mg daily. The few studies of short term DHM therapy in humans reported no adverse events or evidence to toxicity to date. DHM is also a prominent component of several herbal medications including Japanese raisin tree and Chinese vine tea and is found in low concentrations in many plants, fruits and seeds.

A: Yes, dihydromyricetin (DHM) may be good for your liver:
Liver protection: DHM may help protect the liver from chemically-induced damage, and may help reduce liver injury caused by alcohol.
Liver function: DHM may help restore and prolong liver function, and may help delay the onset of liver disease.
Liver transplant: DHM may help the new liver perform better after a transplant.

A: These findings indicate that DHM helps to reduce anxious behaviour, more so than benzodiazepines. Anxious behaviour was also assessed via an open field test. This assessment also tests for anxious aversion to open spaces, physical strength levels, as well as exploratory behaviour.

A: Dihydromyricetin alleviates acute hepatic injury and hepatocyte necrosis, and promotes liver regeneration. Dihydromyricetin counteracts ethanol intoxication, and attenuates alcohol-induced liver injury. Dihydromyricetin ameliorates nonalcoholic fatty liver disease via multiple mechanisms. Dihydromyricetin is a novel adjuvant chemotherapy agent targeting hepatocellular carcinoma through multiple mechanisms.

A: DHM is a flavonoid that's now being marketed as a hangover remedy. Early studies suggest DHM may protect against alcohol-related liver damage, but these studies haven't been conducted in humans. DHM supplements have extremely low bioavailability, meaning your body may not absorb enough to experience true benefits.

A: Dihydromyricetin is a naturally occurring flavonoid found in the many plant species and is thought to be the active ingredient of several traditional Japanese, Chinese, and Korean medicines that are used to treat fever, parasite infections, liver diseases, and hangovers.

A: We found that DHM can inhibit the expression of TIM, Pi3k, and TOR, then decrease Tsc1, while simultaneously promoting FoxO and Thor. In conclusion, DHM could be used as an effective intervention for enhancing sleep quality and counteracting the detrimental of sleep deprivation on lifespan.

A: We recommend taking 300-600 (1-2 capsules) per three drinks of alcohol consumed (one beer or one shot). Please keep in mind Dihydromyricetin (DHM), works much better when taking while or immediately after drinking. It does not have much of an effect when taken the morning after.

A: Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

A: When you consume DHM by mouth—such as through capsules or beverages—very little is absorbed into the bloodstream where it can be used. DHM has about a 5% bioavailability, meaning for every 1,000 mg of DHM consumed, only around 50 mg enters the bloodstream. This is why our capsules contain industry-leading amounts of DHM per dose (1,200 mg, to be exact!).

A: Biologically, recent studies have demonstrated that dihydromyricetin shows multiple health-benefiting activities, including antioxidative, anti-inflammatory, anticancer, antimicrobial, cell death-mediating, and lipid and glucose-metabolism-regulatory activities.

A: Building evidence suggests that dihydromyricetin (DHM), a bioactive flavonoid isolated from Hovenia dulcis, provides hepatoprotection by enhancing ethanol metabolism in the liver by maintaining hepatocellular bioenergetics, reductions of oxidative stress, and activating lipid oxidation pathways.

A: The few studies of short term DHM therapy in humans reported no adverse events or evidence to toxicity. DHM is also a prominent component of several herbal medications including Japanese raisin tree and Chinese vine tea and is found in low concentrations in many plants, fruits and seeds.

A: This means DHM can stabilize GABAergic activity and prevent the excessive dopamine release that's typically triggered by alcohol, which may reduce the rewarding effects of alcohol, mood swings, and potentially alcohol dependence.

A: As a new type of natural flavonoids, dihydromyricetin (DMY) has attracted more and more attention. It has a series of pharmacological effects, such as anti-inflammatory, anti-tumor, anti-oxidation, antibacterial and so on, and it is almost no toxicity and with excellent safety.

A: DHM is not approved for any use or disease in humans in the United States but is available in nutrition centers and on the internet. The typical dose in 300 to 1000 mg daily. The few studies of short term DHM therapy in humans reported no adverse events or evidence to toxicity to date.

A: Dihydromyricetin (DHM) is a natural compound extracted from the Japanese raisin tree. It's been used for centuries as a health supplement in many Asian countries, but it has only recently started gaining popularity in the West.

A: Dihydromyricetin (DHM) is an herbal remedy that may have a number of effects on the body, including:
· Liver health: DHM may protect the liver from damage caused by chemicals and alcohol. It may also help with nonalcoholic fatty liver disease and alcoholic liver disease. DHM may help the body metabolize alcohol faster, reduce fat in the liver, and reduce inflammatory agents.
· Hangovers: DHM may help prevent hangovers. Some say that taking 300–600 mg of DHM after every 3 alcoholic drinks can help prevent hangovers.
· Anxiety: DHM may help improve anxious behavior in mice.
· Other conditions: DHM may also have anti-inflammatory, antioxidant, antibacterial, and antineoplastic properties.