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The Chemical Composition of Centella Asiatica Extract
Apr 28, 2020

Total saponins from centella asiatica are the general name of saponins extracted from centella asiatica, mainly composed of triterpenoid glycosides, of which the representative components are mainly (Aisaticoside, CAS No. : 16830-15-2) and Asaiticoside A.Madecassoside, CAS No. : 34540-22-2) and  Asaiticoside B, CAS No. : 125265-68-1.

 Gotu Kola Extract

Centroside A is also called hydroxycentroside, and centroside B and centroside A are A pair of isomers.

Centella asiatica glycosides A and centella asiatica glycosides B compared with centella asiatica glycosides have one more hydroxyl, polarity difference is bigger, and more easily achieve separation, but centella asiatica glycosides A and centella asiatica glycosides B difference is only one of the methyl belonging to different, and two different belongs in the ortho position relations, the difference in R (Glu - Glu - Rha sugar key) under the influence is more small, so the centella asiatica glycosides A and centella asiatica glycosides B is very difficult to separate.

 Asiatica saponin

The mixture of centroside A and centroside B can promote wound healing, anti-wrinkle, anti-inflammation, anti-depression and intelligence.

By comparing the pharmacological effects of centroside in promoting wound healing and treating scars, it can be found that the pharmacological effects of total saponins of centroside in promoting inflammation, depression and intelligence may be the main effects of centroside A and centroside B.

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