Production Introduction
Indole-3-carbinol, also know as I3C, can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greensand kale.l3C, a precursor to DIM, helps to metabolize excess estrogen, regulates estrogen production, and helps to maintain a healthy hormone balance in both men and women.
Specification
Appearance | Off-white crystal powder |
Identification | HPLC, NMR |
Loss on Drying | ≤1.0% |
Melting point | 88℃ ～ 94℃ |
Total Ash | ≤5.0% |
Residual on Ignition | ≤3.0% |
Residual Solvents | Ethanol≤ 0.5% |
Benzene | |
Total Plate Count | ≤1000cfu/g |
Total Heavy Metals | ≤10.0ppm |
Flow Chart
Mechanism
Indol 3 carbinol or DIM exposures appear to inhibit tumor cell growth via multiple cancer processes.
Evidence that the observed alterations in cell growth-related genes may arise from the interactions between I3C/DIM and the promoter activities of various transcription factors including ERa,Sp1, NFnB and AhR already exists.
Dosage & Formulation
For treating abnormal cells on the surface of the cervix (cervical dysplasia):
Use i3 carbinol 200-400 mg per day has been used.
However, 200 mg seems to be as effective as the higher dose.
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Feature & Advantage
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