NMN——A metabolism to promote cellular energy

NMN, or Nicotinamide Mononucleotide, is a naturally occurring compound that plays a crucial role in cellular energy production. It is a derivative of niacin, also known as vitamin B3. NMN is involved in the production of a molecule called NAD+ (Nicotinamide Adenine Dinucleotide). NAD+ is important for various cellular functions, including DNA repair and maintenance, metabolism, and overall cellular health. NMN is often used as a supplement to support healthy aging and promote cellular energy metabolism.

1. Activation of SIRT protein

Sirtuins play a major regulatory role in almost all cellular functions, affecting physiological processes such as inflammation, cell growth, circadian rhythm, energy metabolism, neuronal function, and mitochondrial regeneration.

Because of such important role of Sirtuins, they are called the longevity protein family, which is a family of NAD+-dependent deacetylase proteins. Studies have found that NMN is an important precursor of NAD+ synthesis in vivo. After it increases the level of intracellular NAD+, many of its effects, such as improving metabolism and protecting cardiovascular, are achieved by activating Sirtuins.

2. Repair DNA damage

DNA repair may sound fantastic, but in fact it is a normal physiological activity of cells that occurs all the time. Under the influence of the outside world, cells will be damaged at the gene level when they carry out metabolic activities. If left unchecked, in addition to losing normal physiological activities, they may also become cancerous.

3. Improve sleep

According to a survey released by the China Sleep Research Association, the incidence of insomnia among adults in my country is as high as 38.2%. There are many reasons for insomnia. As we age and the pressure of life and work increases, our body is more prone to sleep problems.

4. Promote metabolism

Metabolism is a collection of chemical reactions that sustain life in an organism, and is the general term for chemical reactions that sustain life in an organism. NAD+ is an important coenzyme of the tricarboxylic acid cycle in the metabolic process of cellular substances, supplementing NAD+ will promote the body to produce more energy while metabolizing energy substances (glucose, fat and protein). The effect that can be felt intuitively is that the cell metabolism is accelerated and the function is enhanced.

5. Improve the cardiovascular system

Cardiovascular and cerebrovascular diseases are currently the leading non-communicable diseases causing death, and it is estimated that by 2030, the total number of deaths from cardiovascular diseases will exceed 23 million. In recent years, cardiovascular disease tends to be younger, and patients aged 30-50 have become more and more common.

Studies have found that NMN supplementation has a good protective effect on blood vessels. NMN supplementation can reduce vascular oxidative stress, improve aortic sclerosis and vascular dysfunction, restore the activity of arterial Sirt1.

6. Improve female fertility

Due to the increasing social pressure and more and more independent women, more and more people are getting married at a later age and have missed the best reproductive age. An experimental report published by Columbia University in the United States showed that after the age of 35, the number and quality of eggs began to decline for most women.