1. Introduction
The fruit of the horse chestnut contains a large amount of saponin, called esculin. The seeds of the Chinese horse chestnut are a kind of traditional Chinese medicine, which is called the scorpion, so sometimes the Chinese horse chestnut is also called the scorpion tree.
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2.Specification
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Identification |
TLC |
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Assay (UV & HPLC) |
20%, 40%, 98%, 99% |
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Appearance |
Brown powder or White Powder |
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Loss on Drying |
≦5.0% |
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Ash content |
≦5.0% |
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Residual Solvent |
Ethanol ≦5000ppm |
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Total Heavy Metals |
≤10ppm |
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Total Plate Count |
≤5000cfu/g |
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Total Yeast & Mold |
≤100cfu/g |
3.Pharmacological Action
■Animal experiments have shown that it has anti-inflammatory, anti-exudation, increased venous tone, improved blood circulation and correction of brain dysfunction.
■ Horse chestnut seed extract has obvious inhibitory effects on experimental toe edema caused by protein, carrageenan and dextran, and granuloma caused by cotton ball or formaldehyde filter paper.
■ It has obvious protective effects on animals such as carbon monoxide that cause brain edema.
4.Function
■ Aescin has been shown to promote circulation through the veins.
■ Aesculus hippocastanum seed extract possesses anti-inflammatory properties
■ It inhibits the enzyme hyaluronidase and makes veins less permeable and less fragile.

5. Application
■ Horse chestnut extract is popular in Europe for the treatment of chronic venous insufficiency, lesser extent, and varicose veins.
■ It has been shown to reduce post-traumatic edema (liquid swelling), especially after sports injuries, surgery, and head injuries.
■ Having the effect of removing edema, antifatigue, and easing the pressure, esculin is widely used in the health industry.
■ The horse chestnut supplement can be used in cosmetics because it has anti-inflammatory skin effects.
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