What is Hyaluronic Acid Powder Bulk?
Hyaluronic Acid Powder Bulk is a mucopolysaccharide, which widely exists in the extracellular matrix of human and vertebrate tissues and the capsule of some streptococcus, and has important physiological and pharmacological effects; the chemical structure is a linear large chain composed of a disaccharide repeating unit. Molecular polysaccharide, the chemical structure is a linear macromolecular polysaccharide composed of disaccharide repeating units, with a molecular weight of 10,000-4 million Da. Each HA molecule is composed of 30-10,000 disaccharide units.
Specification of Sodium Hyaluronate Powder
|
Product Name |
Hyaluronic Acid Powder |
|
Other Name |
HA, Hyaluronan, Sodium Hyaluronate |
|
Appearance |
White Powder |
|
Origin |
Fermentation |
|
The appearance of 0.5% aqueous solution |
Clear to a slightly opalescent, colorless solution |
|
Clarity of 1% aqueous solution (660 nm, 1 cm) |
< 0.010 |
|
Loss on drying (%) |
≤ 10.0 |
|
Molecular weight (MDA) |
0.2 – 2.2 |
|
Protein (%) |
≤ 0.1 |
|
Microbial contamination (CFU/g) |
< 100 |
|
Hyaluronic Acid (%) |
> 95.0 |
|
Glucuronic acid (%) |
> 45.0 |
Detection
1. Content Detection
Glucuronic acid content: 42%~48%
Pure theoretical content = 194.1/401.3 = 48.37%
glucuronic acid molecular weight = 194.1
Disaccharide unit molecular weight = 401.3
HA content = glucuronic acid content x 2.0675
87 ~ 99%
2. Molecular weight detection
The numerical value of molecular weight obtained by measuring intrinsic viscosity
M.W.=[(ŋ)/3.6×10-4]1.282
3. Viscosity detection
Testing with specialized viscosity agent
Hyaluronic Powder Benefits
1. Cosmetics
Hyaluronic Acid Powder Bulk is the ideal natural moisturizing factor added to cosmetics. It can be used in almost all cosmetics, such as creams, lotions, masks, essences, etc. It can also be used in shampoo, hair care, mousse, facial cleanser, and other products.
2. Food
It can be directly used to produce functional snacks, beverages, and so on.
3. Health products
It can be used as a raw material for health products to produce health products with special properties.
4. Medicine
The compound formed by the reaction of hyaluronic acid and other drugs exerts a sustained release effect on the drug and can achieve the purpose of directional and timed release.
It can be used as a viscoelastic agent for ophthalmic intraocular lens implantation surgery, as a filler for joint surgery such as osteoarthritis and rheumatoid arthritis, and is widely used in eye drops as a medium, and is also used to prevent postoperative adhesions and promote Healing of skin wounds.
It can promote the proliferation and migration of fibroblasts, induce the formation of blood vessels, activate macrophages, and activate lymphocytes.
Advantages of Different Molecular Weight
| HA with different M.W | M.W Range/ Dalton(Da) | Assay by HPLC | Efficiency |
| High M.W | >2.00×106 1.50×106-2.00×106 |
≥95% | High water retention, promote the regeneration of cell tissue. Lubricating and film-forming, moisturizing, preventing skin damage, thickening, and keeping the emulsion stable. |
| Ordinary M.W | 0.8×106-1.30×106 | ≥95% | Lubricating and film-forming, moisturizing, Keep skin moisture and lubrication for a long time. |
| Low M.W | 0.50×106 -0.80×106 0.10×106-0.50×106 |
≥95% | Nourishing the skin, long-lasting moisturizing, easily absorbed by skin, increases skin nutrition. |
| Oligo HA | 7K-10K 3K-5K |
95%-105% | Trans-dermal absorption, deep hydrating, enhancing skin elasticity, strengthening the skin barrier, reducing skin wrinkles, anti-aging, and repairing skin damage. |
Dosage & Formula
|
Function |
Reference Formula |
|
Hydration Moisturizing |
+ beta-carotene/ ascorbic acid/ Vitamin E |
| + Aloe vera freeze-dried powder 200:1/ collagen/ L-Glutathione | |
|
Anti-inflammatory Anti-wrinkle |
+ Grape seed extract/ niacinamide/ lycopene |
| + DMAE/ Vitamin C |
Where can I Buy Hyaluronic Acid Powder?
Natural Field is a cosmetic grade hyaluronic acid supplier and sodium hyaluronic acid powder manufacturer. Factory wholesale sodium hyaluronic acid powder price. We offer the best hyaluronic acid powder at wholesale price. And its hyaluronic acid powder bulk and wholesale sodium hyaluronic acid powder have been lab-tested and verified for both product purity and identity.
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