Calcium Alpha-Ketoglutarate is a naturally occurring compound in the human body. It is one of two keto derivatives of glutaric acid, known for its involvement in various metabolic processes. The substance typically appears as a white crystalline powder that dissolves easily in water, making it convenient for biological functions and supplement formulations.
A key role of it is participation in the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle. This vital biochemical pathway is crucial for energy production and the synthesis of amino acids, which are essential building blocks for proteins.
In addition to its metabolic functions, Calcium Alpha Ketoglutarate is often utilized as a dietary supplement. Its benefits include promoting muscle growth by providing necessary substrates for protein synthesis. Moreover, it supports wound healing by enhancing tissue repair and regeneration processes.

Supplementing with AKG powder can provide several health benefits that enhance overall well-being. Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle, crucial for energy production in our cells. By supporting cellular energy metabolism, AKG helps improve endurance and reduce fatigue, making it especially beneficial for athletes and active individuals.
Many athletes and individuals seeking improved physical performance and recovery turn to this compound to bolster their fitness regimens. Beyond athletic use, its role in supporting overall health has made it an area of interest in nutritional science and supplementation.
Specification
|
Product Name |
Alpha-Ketoglutarate |
|
Specification |
≥98% by HPLC |
|
Standard |
In-house Standard |
|
Appearance |
White crystalline powder |
|
Loss on Drying |
0.3% |
|
Heavy Metals |
≤10.0ppm |
|
Total plate Count |
≤1000cfu/g |
|
Yeast & Mold |
≤100cfu/g |

AKG plays a vital role in amino acid metabolism. This promotes protein synthesis and supports muscle growth and recovery after exercise. For those looking to maintain or build muscle mass, incorporating AKG into their routine can be highly advantageous.
With increasing age, the level of alpha-ketoglutarate in the human body will gradually decrease. Exercise can increase AKG levels and promote the healthy development of the human body. However, AKG is not present in the normal diet, so supplementing with the right amount of AKG powder is essential to protect your health.
Benefits
1. Tricarboxylic acid cycle
It is an important metabolic intermediate in the microbial tricarboxylic acid cycle, located after isocitrate and before succinyl-CoA. The apoplastic reaction can achieve the purpose of supplementing this intermediate metabolite by generating α-ketoglutarate from the transamination of glutamate.
2. Production of amino acids
Glutamate is mainly synthesized by α-ketoglutarate by transaminase and glutamine by glutaminase. Glutamate is metabolized back to α-ketoglutarate by glutamate dehydrogenase (GDH).
3. Build muscle and improve athletic performance
It has muscle-building properties, improved muscle mass, and improved athletic performance.
4. Antioxidants
It released by several cell types reduces the levels of hydrogen peroxide, and alpha-ketoglutarate is depleted in the cell culture medium and converted to succinate.
AKG has also been shown to help support cardiovascular health, such as improving circulation and decreasing oxidative stress levels, which contributes to heart maintenance as well as protective effects against age-related decline. Due to these properties, its potential anti-aging benefits make AKG an appealing option for anyone interested in longevity support.
AKG can aid bone health by increasing calcium absorption and collagen synthesis for stronger bones - particularly important for older adults at increased risk of osteoporosis. Overall, supplementing with AKG powder provides comprehensive support to many bodily functions essential to optimal wellbeing.
Application
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1.Food and Drink
Used as a food additive, mainly as an ingredient in sports nutrition drinks
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2.Health Products
Calcium-α-ketoglutarate can be used as a health supplement
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3.Cosmetics
Alpha-ketoglutarate has an antioxidant effect, scavenges the damage caused by free radicals to the skin, and delays aging.
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