Xi'an Natural Field Bio-Technique Co.,Ltd.
Categories
Contact Us

Sales Department:

Whatsapp: 8618191853912

Tel: +86-29-87973630

Skype:  sales19@natural-field.com

Email:info@natural-field.com


HEADQUARTERS ADDRESS:

5th Floor, Building B, No.57,Keji 3rd Road,High-Tech Zone, Xi'an,710075,China

FACTORY ADDRESS:

No 6, Caotang Industry Park, No.2 Qinling Road, Hi-tech Zone, Xi'an, China

Silymarin Extract

Silymarin Extract

Product name: Silymarin
Chemical formula: C25H22O10
Molecular weight: 482.436
Appearance: yellow or brown powder
CAS: 65666-07-1
EINECS: 613-830-9
Main functions: protect the liver, anti-tumor, etc.
...
Chat Now

What is Silymarin?

Silybum marianum (L.) Gaertn is a plant of the genus Silybum in the Compositae family, which is native to southern Europe and North Africa. Silymarin is a natural active substance extracted from the dried fruit of Silybum marianum. The main components are silybin, isosilybin, silydianin and silybin. silychristin), silybin and isosilybin are two pairs of corresponding isomers. Among them, silybin has the highest content, accounting for 60% to 70%, and has the strongest activity. Silymarin extract is light yellow to brownish-yellow powder, insoluble in water and chloroform, but easily soluble in solvents such as methanol, ethanol, ethyl acetate, acetone, etc.

silymarinmilk thistle supplement

Item

Specification

Result

Assay of silymarin(UV test,percent,Standard in house)

≥80.00%

Conforms

Assay of silymarin(test by HPLC)

USP

34.72%

Sum of silycristin and silydianin(test by HPLC)

USP

15.20%

Sum of silybin A and silybin B(test by HPLC)

USP

13.00%

Sum of isosilybin A and isosilybin B(test by HPLC)

USP

6.52%

Physical Characteristics



Appearance

Amorphous Powder

Conforms

Odor

Slight,Specific

Conforms

Solubility in water

Practically Insoluble

Conforms

Solubility in Methanol and Acetone

Soluble

Conforms

Identification

HPLC

Conforms

Sulphated Ash

≤0.5%

Conforms

Loss on drying(2 hours 105°C)

≤5.0%

Conforms

Powder size

≥90% through 80 mesh

Conforms

Heavy metals

≤10ppm

Conforms

Arsenic

≤3.0ppm

Conforms

Lead

≤1.0ppm

Conforms

Mercury

≤0.1ppm

Conforms

Cadmium

≤1.5ppm

Conforms

Microbiological Tests



Total Plate Count

≤1000cfu/g

Conforms

Total Yeast & Mold

≤100cfu/g

Conforms

E.Coli

Negative

Negative

Salmonella

Negative

Negative

Staphylococcus

Negative

Negative

storage

In Tight,Light-resistant and dry place,Avoid direct sunshine.

Silymarin Benefits:

1. Liver protection

Silymarin mainly eliminates free radicals through anti-lipid peroxidation, increases the level of glutathione (G-SH) in the liver, and plays a hepatoprotective effect.

2. Anti-cancer activity

Silymarin can be used to treat breast cancer, bladder cancer, oral cancer, cervical cancer, colon cancer, ovarian cancer, lung cancer, pancreatic cancer, gastric cancer, etc. Silymarin and silibinin regulate the imbalance of cell survival and apoptosis by interfering with cell cycle regulation and proteins involved in cell apoptosis.

3. Hypoglycemic effect

Increased glucose and fatty acid levels in diabetic patients lead to increased ROS, accompanied by insulin resistance and pancreatic J3 cell dysfunction, and silymarin can significantly improve the above symptoms.

4. Treatment of neurodegenerative diseases

Silymarin can inhibit the activation of MAO glial cells, stimulate the secretion of peroxide products, promote ribosomal RNA synthesis, alleviate neuronal oxidative damage, and treat Parkinson's and other neurodegenerative diseases.

5. Immune regulation

Silymarin can significantly inhibit the proliferation of CD4+ cells and the production of IL 2 and IFN 7, especially the NF KB activation/translocation pathway, showing the potential for immunoregulation; it can also inhibit the production of TNF a, IL 10, TNF B1, PGE2 and NO. Shows anti-inflammatory effects.


Is silymarin safe?

The silymarin drug is safe and will not cause gastrointestinal disorders, allergic reactions, urticaria, nausea, headache, joint pain, skin itching, diarrhea, and other adverse reactions after taking it. There are many types of silymarin-related hepatoprotective drugs, such as Lijialong in Germany, Silybum marianum extract capsules in the United States, Yiganling, Gantai capsules, and silibinin meglumine tablets in China, all of which are widely used in clinical practice.

If you want to know more, please consult info@natural-field.com

natural field factory

Natural-Field certifications

Hot Tags: silymarin extract, manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk

Previous: No Information

Next: Silymarin From Milk Thistle

Related Products