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Product name: Milk thistle extract
Active ingredient: Silybin
Botanical Source: Seed of Silybum marianum
Specification:30%, 35%, 40%, 80%
Molecular Formula: C25H22O10
Molecular Weight: 482.44
Silybin, isolated from Milk thistle, also known as Silybum marianum, is an annual or biennial plant of the Asteraceae family. This rather typical scorpion has red to purple flowers and shiny light green leaves with white veins. It is native to southern Europe and continues to Asia and is now global.
Silymarin, a natural flavonol lignan compound, is a natural active substance extracted from the dried fruit of Compositae dairy products. Its main components are silybin and isoflavone. Silymarin is almost insoluble in water, soluble in acetone, ethyl acetate, methanolic ethanol, and slightly soluble in chloroform.
Assay(UV / HPLC)
30%, 35%, 40%, 80%
Light yellow powder
Loss on Drying
Total Heavy Metals
Total Plate Count
Total Yeast & Mold
It has been confirmed in various pathological models of toxic liver damage. Silymarin can neutralize poisoning caused by chlorpyrifos, alpha-amanita (toxic substances found in Gypsophila amanita fungi), carbon tetrachloride, galactosamine, thioacetamide and hepatic virus FV3.
The therapeutic effect of silymarin is attributed to its multiple action points and mechanism of action due to its ability to capture free radicals. Silymarin has anti-peroxidation activity. The pathophysiological process of lipid peroxidation (causing damage to the cell membrane) can be blocked or blocked by silymarin. And in hepatocytes that have suffered damage, silymarin stimulates protein synthesis and normalizes phospholipid metabolism.
In short, the biggest contribution of silymarin is to stabilize the liver cell membrane. It prevents or avoids the loss of soluble cellular components such as transaminase. Silymarin can limit the penetration of certain hepatotoxic substances (such as alpha-amanita) into the interior of cells. The enhancement of protein synthesis is due to the fact that silymarin stimulates the activity of RNA polymerase I in the nucleus, thus helping the synthesis of ribosomal RNA in hepatocytes, and at the same time leading to the massive synthesis of structural and functional proteins (enzymes). Therefore, silymarin can enhance the repair ability and regenerative capacity of hepatocytes.
This substance has the following effects. It can protect liver cells from toxic substances, especially alcohol and environmental pollutants (insecticides, heavy metals, etc.) invading the liver. It has strong antioxidant function and protects liver cells from free radical damage. Far better than vitamin E. It promotes protein synthesis, accelerates the production of new hepatocytes, or repairs damaged liver cells themselves. Therefore, it is called "natural liver protection medicine". In addition, silymarin also has anti-radiation, anti-aging, prevention and treatment of arteriosclerosis, delaying skin aging and other effects. This product is widely used in the production of medicines, health products, cosmetics, food and other products. The current silymarin dosage form has oral preparations: silymarin tablets, Yiganling tablets, silybin lecithin composite hard capsules.
1. Silibinin can reduce growth of cancer cells in breast, cervical, and prostate cancers
2. Silibinin extract is mainly used for viral hepatitis, acute and chronic hepatitis, cirrhosis, fatty liver, nutrition, metabolic disorders and cardiovascular disease.
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