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Standardized Extract

Hovenia Dulcis Extract Dihydromyricetin 10% 20%

Hovenia Dulcis Extract Dihydromyricetin 10% 20%

Product Code: NF-017
Botanical Source: Seed of Hovenia Dulcis
Active ingredient: Dihydromyricetin
Specification: 10%, 20%
Certifications: ISO, KOSHER, HACCP, CQC...
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Hovenia Dulcis Extract Dihydromyricetin 10% 20% Details

Active Ingredient: Dihydromyricetin

Botanical Source: Hovenia Dulcis

Appearance: Brown powder

Main Specification: 10%, 20%


Hovenia Dulcis Extract Dihydromyricetin 10% 20% Oil Introduction

Hovenia dulcis, an oriental raisin tree, is a cold-tolerant tree found in eastern China. Fruit can also be eaten.

It has been used in traditional Japanese, Chinese and Korean medicines to treat fever, parasitic infections, as laxatives, to treat liver disease, and as a hangover treatment.

Dihydromyricetin is a woody vine that is extracted from the genus Vitis and is also extracted from jujube. The main active ingredient is flavonoids, which have the ability to scavenge free radicals, anti-oxidation, anti-thrombosis and anti-thrombosis, and have special effects on tumors and anti-inflammatory. Dihydromyricetin is a special flavonoid compound. In addition to the general characteristics of flavonoids, it also has alcoholic toxicity, which will alleviate the effects of alcoholic liver, fatty liver and liver cells, and reduce the incidence of liver cancer. It is protection. Good product for the liver, liver protection, hangover and sobriety.


Specification of Hovenia Dulcis Extract Dihydromyricetin 10% 20%

Identification

TLC

Assay (TLC, HPLC)

10%, 20%

Appearance

Brown to Off-white powder

Loss on Drying

≦5.0%

Ash content

≦5.0%

Residual Solvent

Ethanol≦5000ppm

Total Heavy Metals

≤10ppm

As

≤2ppm

Pb

≤2ppm

Hg

≤0.1ppm

Cd

≤1ppm

Total Plate Count

≤5000cfu/g

Total Yeast & Mold

≤100cfu/g


Main Functions

1. Hovenia Dulcis Seed Extract could be used in anti-hangover medicine, counteracts acute alcohol intoxication and withdrawal symptoms;

2. Hovenia berry extract have the effect of sedative sober.

3. Hovenia dulcis dihydromyricetin as ingredients for anti-Alcohol Supplement, drink and tea etc.

Dihydromyricetin is an extract of Vitis vine tea, which is the main active ingredient flavonoid in vine tea. These substances have many unique effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor and anti-inflammatory. Dihydromyricetin is a special flavonoid compound that relieves alcoholism, prevents alcoholic liver, fatty liver, inhibits hepatocyte deterioration, reduces the incidence of liver cancer, antihypertensive, inhibits platelet aggregation in vitro and thrombosis in vivo. It has special effects in forming, lowering blood lipids and blood sugar levels, improving SOD activity, and protecting liver and protecting liver.

Antibacterial effect: Pharmacological experiments show that dihydromyricetin against Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, Aerobacteria, Saccharomyces cerevisiae, Red yeast, Penicillium, Aspergillus niger, Aspergillus flavus, hair Both mildew and rhizopus have antibacterial effects, especially for Gram-positive, Gram-negative cocci or bacilli.

Regulation of blood sugar and blood lipids: Pharmacological experiments in mice showed that dihydromyricetin can significantly inhibit the increase of blood glucose in mice induced by alloxan, adrenaline, streptozotocin, etc., and increase serum insulin levels. Lymphocyte infiltration was significantly reduced in the pancreatic tissue, the inflammatory response was significantly reduced, and the number of islets was significantly increased. Dihydromyricetin has a reduced effect on serum triglyceride (TG) content in rats with hyperglycemia induced by streptozotocin, and has no significant effect on serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL2C).

Liver protection: Dihydromyricetin has a significant protective effect on carbon tetrachloride poisoning injury in rat hepatocytes cultured in vitro, D2 galactosamine and lipopolysaccharide-induced liver injury in mice. Dihydromyricetin can protect the liver and accelerate the rapid decomposition of the ethanol metabolite acetaldehyde into non-toxic substances, reducing its damage to liver cells. In addition, dihydromyricetin can improve the activity of serum lactate dehydrogenase caused by hepatocyte injury, inhibit the formation of hepatic M cell collagen fibers, thereby protecting the liver and protecting the liver, and greatly reducing the damage of ethanol to the liver. The liver's normal state is quickly restored. The Microherb test proved that dihydromyricetin can protect the liver, accelerate the rapid decomposition of the ethanol metabolite acetaldehyde, become non-toxic substances, and reduce damage to liver cells. Dihydromyricetin has a rapid onset and long-lasting effect. It is a good product for protecting the liver and protecting the liver and hangover.

Antioxidant effect: Dihydromyricetin with a purity of 98% can significantly inhibit the formation of malondialdehyde (MDA) in rat myocardium, liver and brain homogenate, and inhibit the formation of MDA with the increase of dihydromyricetin concentration. The effect of 99% dihydromyricetin on the clearance of diphenyltrinitrophenylhydrazine (DPPH) free radicals in the test system. Dihydromyricetin can significantly inhibit the formation of MDA in oils and fats, and the anti-oxidation effect is enhanced with the purity of dihydromyricetin (60%-90%); it has strong anti-oxidation effect on animal oil and vegetable oil.

Anti-tumor effect: In recent years, anti-tumor pharmacodynamics research found that one of its active ingredients, snake glucosin small molecule compound has a strong anti-cancer effect. In vitro anti-tumor effect studies have found that this compound can improve the therapeutic effect of tumors and improve the life-threatening symptoms of patients by inhibiting tumor blood vessel growth and regulating cellular immune function. It is used in tumor model tests such as leukemia and nasopharyngeal carcinoma. It shows obvious anti-tumor effect.

The scented snake grape, also known as vine tea, is a traditional medicine used by the people. It has been widely used to treat infectious diseases such as skin diseases, carbuncles and osteomyelitis, and acute lymphitis. Dihydromyricetin is widely used in Chinese patent medicine preparations for treating respiratory tract infections and alcoholism, such as tablets, capsules and granules. In recent years, anti-tumor pharmacodynamic studies have found that one of its active ingredients, snake glucosinolate small molecule compounds have a strong anti-cancer effect. The research of dihydromyricetin has obtained the invention patent authorization in the application field of preparation of anti-leukemia and nasopharyngeal cancer drugs. It has been prepared as a new class of drugs to enter the clinical trial phase. The development of a new Chinese medicine, snake glucosin injection, is expected to provide a new therapeutic drug for patients with leukemia and nasopharyngeal cancer. Microherb completed the extraction and purification techniques of vine tea extract (total flavonoids from the scented snake grape) and dihydromyricetin, and completed related toxicological experiments and efficacy studies, and developed the components with dihydromyricetin as efficacy. The instant tea, the total flavonoids of the toothed snake grape, the dihydromyricetin hangover and the liver-protecting capsule and other health foods.

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