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10-deacetylbaccatin Iii (10-dab)
Description
10-Deacetylbaccatin III (10-DAB) Details
Product name: 10-Deacetylbaccatin III (10-DAB) Specification: 99.5% HPLC Standard: USP 32 Appearance: white crysaline powder | Botanical source: Taxus Baccata Mole formular: C29H36O10 CAS No.: 32981-86-5 Mole weight: 544.597 |
10-deacetylbaccatin Iii (10-dab) Oil Introduction
It is a natural organic compound isolated from the Pacific yew tree (Taxus) and related species.10-DAB III is a white to off white crystalline powder, insoluble in water.
10-DeacetylbaccatinIII or 10-DAB III is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented. By extracting the pre-cursor 10-DAB III in large quantites from the Taxus baccata leaf, many subsequent semiayntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and therefore the pharmacological profile of these important chemo-therapeutic agents.
Specification of 10-Deacetylbaccatin III (10-DAB)
Identification | TLC |
Assay by HPLC | 99% min. |
CAS | 32981-86-5 |
Appearance | White powder |
Extract Solvent | Ethanol & water |
Loss on Drying | ≦2.0% |
Ash content | ≦0.5% |
Residual Solvent | Ethanol<3000ppm |
Total Heavy Metals | ≤10ppm |
As | ≤1ppm |
Pb | ≤1ppm |
Hg | ≤0.1ppm |
Cd | ≤1ppm |
Total Plate Count | ≤1000cfu/g |
Total Yeast & Mold | ≤100cfu/g |
Main Functions
Anti-Cancer for drug raw material.
