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What is apigenin extract?
For centuries, some plants containing apigenin have been used as Chinese medicine ingredients to treat neuralgia, Parkinson's disease, asthma, and other diseases. It was not until the 1960s that scientists gradually paid attention to the molecular mechanism of various biological activities of apigenin. The 3 hydroxyl groups at positions 4', 5, and 7 and double bonds at positions C2 and C3 in the apigenin molecule can be combined with free radicals. , The 7-position hydroxyl group can chelate metal ions and inhibit the production of free radicals, thereby determining the antioxidant activity of apigenin; in addition, apigenin can also reduce blood pressure and blood lipids, protect the cerebral ischemia-reperfusion injury, anti-inflammatory, and sterilize And other pharmacological activities. Therefore, people's demand for apigenin extract is also increasing.
1 Anti-tumor effect
●Regulate the tumor cell cycle
●Promote apoptosis and autophagy
●Inhibition of invasion and metastasis
●Impact on cell adhesion molecules
●Induce cancer cell differentiation
●Inhibit tumor angiogenesis
2 It has a protective effect on the heart and brain blood vessels
●Alleviate ischemia-reperfusion injury
●Improve high blood pressure and complications
3 Anti-neurodegenerative diseases
4. Anti-type 2 diabetes
●Protect the function of pancreatic β-cells
●Act on PPARγ, α-glucosidase and other hypoglycemic targets
Is apigenin safe?
Apigenin is an ingredient in the daily diet, which is widely found in many kinds of vegetables, fruits, and legumes. Scientists have systematically studied the acute toxicity, subchronic toxicity, and genetic toxicity of apigenin. The maximum tolerated dose (MTD) for acute toxicity of apigenin in rats is greater than 8 g/kg body weight; the level of no obvious damage in the 90-day feeding experiment of apigenin in rats is 8 g/kg body weight; using Ames experiment, mouse bone marrow The micronucleus experiment and the mouse sperm cell malformation experiment system studied the genetic toxicity of apigenin, and the results showed no genetic toxicity, suggesting the good biological safety of apigenin.
Why choose us to buy Apigenin extract?
1. Quality Assurance
Reduce disputes caused by quality problems, avoid complex procedures.
2. Guarantee Function
We ensure our product's active ingredient is guaranteed, and have fantasy appraise.
3. Efficient Team
Effective coordinate of all departments in 24 hours, quickly reply your every question.
Production record data of each batch is kept intact, including raw materials, solvents, packing, CCP, storage, delivery.
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