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Minoxidil is an antihypertensive vasodilator medication. It also slows or stops hair loss and promotes hair regrowth in some people. Now off-patent, it is available over-the-counter for the treatment ofandrogenic alopecia.
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with effects that included hair growth and reversal of male baldness. In the 1980s, UpJohn Corporation came out with a topical solution of 2% minoxidil, called Rogaine, for the specific treatment of androgenetic alopecia. Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure.
Minoxidil is currently the only topical chemical in the world that has a significant effect on hair loss. This medicine is used to lower blood pressure. If the external large dose is used, the drug will penetrate into the body through the skin and may cause headache and hypotension. If you accidentally drop it on your face, it may cause the hair to grow too much. But it is precisely because "Minodol" is currently the only topical chemical in the world that has obvious curative effect on hair loss. Therefore, experts say that many ingredients in the market currently contain this ingredient.
Minoxidil is a potassium channel opener, which can directly relax vascular smooth muscle, has a strong expansion of small arteries, reduces peripheral resistance, lowers blood pressure, and has no effect on volumetric blood vessels, so it can promote venous return. At the same time, due to the reflex regulation and positive frequency, the cardiac output and heart rate can be increased, but no orthostatic hypotension is caused.
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