Luteolin, 3',4',5,7-tetrahydroxyflavone or luteolin-7-o-glucoside, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Luteolin benefits of flavonoids is known for its many health benefits, such as antioxidants and antimicrobial agents, especially the luteolin powder. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and cancer.

Luteolin mechanism of action

Having multiple biological effects such as anti-inflammation, anti-allergy and anticancer, luteolin functions as either an antioxidant or a pro-oxidant biochemically. The luteolin mechanism of action could be functionally related to each other. For instance, the anti-inflammatory activity may be linked to its anticancer property. Luteolin's anticancer property is associated with the induction of apoptosis, and inhibition of cell proliferation, metastasis and angiogenesis. Furthermore, luteolin sensitizes cancer cells to therapeutic-induced cytotoxicity through suppressing cell survival pathways such as phosphatidylinositol 3'-kinase (PI3K)/Akt, nuclear factor kappa B (NF-kappaB), and X-linked inhibitor of apoptosis protein (XIAP), and stimulating apoptosis pathways including those that induce the tumor suppressor p53.

The luteolin medicinal uses suggest that luteolin could be an anticancer agent for various cancers. Furthermore, recent epidemiological studies have attributed a cancer prevention property to luteolin.

Where to buy luteolin?

Xi'an Natural Field Bio-Technique Co.,Ltd. as Luteolin Manufacturer, which is the professional Manufacturer of Herbal Extract Since 2005. They focus on researching and producing the Luteolin and Apigenin. Our high purity active ingredients is tested by HPLC. therefore, Luteolin hplc 98% and apigenin hplc 98% are standard specitication. If you need these products, please contact us or send an inquiry to info@natural-field.com at any time.