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Test Results——Polygonum Cuspidatum Extract on Wound Healing
Oct 07, 2017

Polygonum cuspidatum (Main ingredients: resveratrol, Polydatin) has long been used as a traditional medicine inducing wound healing. In this study, the extract from the Chinese medicinal herb Polygonum cuspidatum was investigated on polygonum cuspidatum extract wound healing activity, in order to obtain an accurate elucidation of its traditional use value.

Mamterial and Methods:

After creating wound healing model on the back of rats, the extract from the Chinese medicinal herb Polygonum cuspidatum was applied. Wound healing rates were calculated at 3, 7, 14, and 21 days after the wounding, and tissues were harvested at 1, 3, 7, 14 and 21 days for histological and immunohistochemistry analysis. The stages of wound granulation tissues were evaluated histopathologically. The expression of TGF-β1 was determined by immunohistochemically.


Wound healing rates were significantly higher at 3, 7, 14 and 21 days in the extract group than in the control (p<0.05). Histological results showed more well-organized bands of collagen, more fibroblasts and hair follicle and less inflammatory cells in the extract group. The immunohistochemical results revealed that TGF-β1 increased in the extract group on day 1, 3 and 7 post-wounding (p<0.05).


The present study has shown that the extract from the Chinese medicinal herb Polygonum cuspidatum possesses wound healing activity, and thus provided the evidence for its traditional use value.

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Xi'an Natural Field Bio-Technique Co.,Ltd. as Polygonum Cuspidatum Extract Manufacturer, which is the professional Manufacturer of Herbal Extract Since 2005. And attend the CPHI, Vitafoods and API Exhibition from 2008. Polygonum Cuspidatum Extract is the one of strong products, we will supply the Polygonum Cuspidatum Extract Price and service to you. If you need this product and related product, please contact us or send an inquiry to info@natural-field.com at any time.