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WHAT IS INDOLE-3-CARBINOL?
Indol 3 carbinol is a chemical, also known as I3C.Is produced by the breakdown of the glucosinolate glucobrassin.Mainly comes from cruciferous vegetables, Broccoli, Brussels sprouts, cabbage, cauliflower, collards, kale and kohlrabi, mustard greens, rapeseed, rutabaga, turnips.
HOW DOES I3C WORK
3 important factors：PTEN，WWP1，WWP1
-PTEN is a tumor suppressor gene that inhibits the development of cancer, but it is also a tumor suppressor gene that is prone to mutation in the body.
If the tumor suppressor gene is also mutated, it will also promote the occurrence of cancer.
-WWP1 is an E3 ubiquitin ligase, which can bind to PTEN, thus affecting its anticancer function.
-I3C can inhibit the function of WWP1, and then inhibit its effect on PTEN and release PTEN, which can restore the inhibiting function of PTEN.
-In acidic gastric environment, I3C is easily converted into DIM (diindolyl methane), which can neutralize free radicals and promote appropriate clear body.
-And studies have shown that I3C supplements can help maintain the health of breasts and other reproductive organs,especially hormone-related cancers such as breast and prostate.
IS I3C BETTER THAN DIM
-Study show that i3c carbinol is unstable in stomach acid .In acidic gastric environment, I3C is easily converted into DIM (diindolyl methane), which can neutralize free radicals and promote appropriate clear body.
-The anti-cancer effects of I3C are due to DIM.
HOW MUCH I3C SHOULD I TAKE
200 mg per day has been used, pls ask your doctor for further suggestions.
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