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Aug 18, 2017


Likely Effective for:

Varicose veins and other circulatory problems (chronic venous insufficiency). Taking horse chestnut extract seed extract containing 16% to 20% of the chemical aescin can reduce some symptoms of poor blood circulation, such as varicose veins, pain, tiredness, swelling in the legs, itching, and water retention. However, some early research suggests that horse chestnut extract might be less effective than Pycnogenol for reducing leg swelling and cramps.

Insufficient Evidence for:

Male infertility. Early research suggests that taking horse chestnut extract seed extract increases sperm density, but not improve sperm movement, in men with fertility problems.





Enlarged prostate.


Menstrual pain.

Soft tissue swelling from bone fracture and sprains, arthritis, joint pain, and other conditions.

Other conditions.

More evidence is needed to rate horse chestnut extract for these uses.


Horse chestnut extract, also named aesculus hippocastanum extract which is LIKELY SAFE for most people when a standardized seed extract product is taken by mouth for a short amount of time. Standardized products have been tested to contain exact amounts of a verified chemical. Look for products which have had the toxic substance esculin removed. Horse chestnut extract products can sometimes cause side effects such as dizziness, headache, stomach upset, and itching.

Pollen from the horse chestnut extract flower can cause allergic reactions. Rectal (suppository) use of horse chestnut extract may cause inflammation and itching in the anal area.

Raw horse chestnut extract seed, bark, flower, and leaf are UNSAFE and can even cause death when taken by mouth by adults or children. Signs of poisoning include stomach upset, kidney problems, muscle twitching, weakness, loss of coordination, enlarged eye pupils, vomiting, diarrhea, depression, paralysis, and stupor. Accidental ingestion of horse chestnut extract requires prompt medical attention. Children have been poisoned by drinking a tea made from the leaves and twigs or eating seeds. 

Special Precautions & Warnings:

Pregnancy and breast-feeding: 

Taking the raw seed, bark, flower or leaf is UNSAFE and can lead to death. Not enough is known about the safety of using horse chestnut extract seed extract from which the poisonous esculin has been removed during pregnancy or breast-feeding. Stay on the safe side and avoid using horse chestnut extract if you are pregnant or nursing.

Bleeding disorders: 

Horse chestnut extract might slow blood clotting. Taking horse chestnut extract might increase the risk of bruising and bleeding in people with bleeding disorders.


Horse chestnut extract might lower blood sugar. If you have diabetes, watch for signs of too low blood sugar (hypoglycemia) and check your blood sugar carefully.

Digestion problems: 

Horse chestnut extract seeds and bark can irritate the gastrointestinal (GI) tract. Don’t use it if you have bowel or stomach disorders.

Liver disease: 

There is one report of liver injury associated with using horse chestnut extract. If you have a liver condition, it is best to avoid horse chestnut extract.

Latex allergy: 

People who are allergic to latex might also be allergic to horse chestnut extract.

Kidney disease: There is a concern that horse chestnut extract might make kidney disease worse. Do not use it if you have kidney problems.


Horse chestnut extract might slot blood clotting. Horse chestnut extract might increase the risk of bleeding if used before surgery. People using horse chestnut extract should stop at least 2 weeks before surgery.


Lithium interacts with HORSE CHESTNUT EXTRACT

Horse chestnut extract might have an effect like a water pill or "diuretic." Taking horse chestnut extract might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.

Medications for diabetes (Antidiabetes drugs) interacts with HORSE CHESTNUT EXTRACT

Horse chestnut extract might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking horse chestnut extract along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with HORSE CHESTNUT EXTRACT EXTRACT. Horse chestnut extract seed might slow blood clotting. Taking horse chestnut extract seed along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.


BY MOUTH(The dose has been studied in scientific research):

For poor blood circulation (chronic venous insufficiency): 300 mg of horse chestnut extract seed extract containing 50 mg of the active ingredient, aescin, twice daily.

Where to buy horse chestnut extract?

Get more plant extractcosmetic raw ingredients and health ingredients

Xi'an Natural Field Bio-Technique Co.,Ltd. as Horse Chestnut Extract Manufacturer, which is the professional Manufacturer of Herbal Extract Since 2005. And attend the CPHI, Vitafoods and API Exhibition from 2008. aesculus hippocastanum seed extract powder is the one of strong products, we will supply our aesculus hippocastanum leaf extract powder price and service to you. horse chestnut extract analysis by hplc and the main specification 20% Aescin and 98% Aescin. Also, we can supply the Sodium Aescinate Powder 98% for customers. If you need this product and related product, please contact us or send an inquiry to [email protected] at any time.

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