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Aloe Emodin——Skin conditioning & Body's Immune Regulation
Jan 20, 2020

Aloe Emodin——Skin conditioning

The repair effect and mechanism of aloe emodin on skin trauma show that aloe-emodin powder can effectively promote wound healing, the dose of 300 ug/mL-1 is the best effect, by increasing the expression level of skin and blood vessel-related growth factors, thus promoting wound healing, is one of its mechanisms.

Effect of aloe vera extract, an active ingredient in jaundice, on the proliferation of fibroblasts in hyperplasia scar tissue, and the results show that aloe emodin inhibits the growth of scar-fibroblasts, which is dose-dependent and time-dependent, and also has dose dependence to reduce fibroblast growth. Progeny index and induced fibroblast apoptosis, thereby reducing scar tissue formation.

The effect of aloe emodin on cell proliferation and apoptosis in human keratin formation shows that aloe-emodin can significantly inhibit the proliferation of keratin cells and induce keratosis. The above results show that aloe emodin can play the role of skin conditioning from many angles.

Aloe Emodin——Body's Immune Regulation

The effect of aloe emodin leukocyte interleukin-2 (IL - 2) caused by t-cell proliferation and changes in intracellular Ca2 plus concentration in rats, and the results showed that aloe-emodin regulates the body's immune function by significantly inhibiting the proliferation of T cells induced by IL -2, and its mechanism of action may be possible with the inhibition of intracellular Ca2 plus The increase in subconcentration is associated.

Aloe-emodin powder enhances the phagocytomy of macrophages and induces the expression of cytokines mRNAs, including leukocyte interleukin 1 beta (IL-1 beta), tumor necrosis factor, and interferon, in white blood cells, thereby enhancing the body's immune function.

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