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Aloe-Emodin——Pathogen-resistant Microorganisms and Anti-inflammatory Effects
Jan 20, 2020

Aloe-emodin has a significant anti-white intake bacteria, Antifungal activity such as new cryptococcal, hairy bacteria and clostridium, It also has a strong inhibitory effect on common anaerobic bacteria in clinical practice. In addition, for E. coli, Bacillus, Staphylococcus aureus, stalphinated spore, copper-green pseudomonas, There is obvious antibacterial activity such as Helicobacter pylori and mycobacterium tuberculosis.


Studies have shown that aloe emodin powder may become clinically antifungal, anti-anaerobic, anti-tuberculosis and auxiliary drugs for the treatment of stomach ulcers.


However, aloe vera extract aloe emodin inhibits the intestines Probiotics such as Bifidobacteria grow and long-term applications can lead to intestinal flora disorders.


The results suggest that aloe-emodin powder, like a drug, should pay attention to the gastrointestinal adverse reactions that may be caused by long-term application. In addition, The antiviral effect of aloe emodin shows that it can reduce the effect of viral-induced cell lesions, and inhibits the replication of influenza A virus with concentration dependence.


The findings suggest that aloe emodin 95 may become a new anti-flow The pharmacological activity of virus-sensitive drugs, such as the highly pathogenic H5N1 avian influenza virus and the new influenza virus H7N9, which threaten human health, needs further study.


The anti-inflammatory effect and mechanism of aloe emodin showed that RAW264 of lipid polysaccharide stimulation can be significantly reduced by inhibiting the expression of induced nitric oxide glycolinease (iNOS) mRNA. 7 Cells released nitric oxide to play anti-inflammatory

Role. The study of the anti-inflammatory effects of aloe emodin is mainly focused on the treatment of severe pancreatitis.


It has been found that the therapeutic effect of aloe emodin on severe acute pancreatitis may be associated with lower levels of platelet activation causes (PAF), leukin-6 (IL-6) and tumor necrosis factor -alpha (TNF-alpha). In addition, aloe emodin powder has a strong inhibitory effect on pancreatic peptide release enzyme and tryptopsin. Pancreatic Enzymes are closely related to the occurrence of pancreatitis, which may be another mechanism for treating pancreatitis in aloe emodin 95 powder.


The above results show that aloe emodin may become a new anti-inflammatory drug, especially in the treatment of severe pancreatitis.


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