Chlorogenic Acid Eucommia Bark Extract Details

Product Code: NF-036

Botanical Source: Eucommia ulmoides Oliv.

Active ingredient: Chlorogenic Acid

Specification: 5% 10% 20% 25% 50% 98%

Chlorogenic Acid Eucommia Bark Extract Oil Introduction

Chlorogenic acid (CGA)/ know as eucommia bark extract, is a natural chemical compound which is the ester of caffeic acid and  (-)-quinic acid. Honeysuckle flower extract / lonicera japonica flower extractis an important biosynthetic intermediate. Chlorogenic acid is an important intermediate in lignin biosynthesis. This compound, known as an antioxidant, may also slow the release of glucose into the bloodstream after meal.

Specification of Chlorogenic Acid Eucommia Bark Extract

Identification	TLC
Assay by HPLC	5% 10% 20% 25% 50% 98%
CAS	327-97-9
Molecular Structure
Appearance	Brown powder or White crystalline powder
Extract Solvent	Ethanol & water
Loss on Drying	≦5% ≦2.0%
Ash content	≦5% ≦0.5%
Residual Solvent	Ethanol<3000ppm
Total Heavy Metals	≤10ppm
As	≤1ppm
Pb	≤1ppm
Hg	≤0.1ppm
Cd	≤1ppm
Total Plate Count	≤1000cfu/g
Total Yeast & Mold	≤100cfu/g

Main Functions

1. Antioxidant, remove free radicals in the body

Chlorogenic acid and its derivatives have stronger free radical scavenging effects than ascorbic acid, caffeic acid and tocopherol (vitamin E), which can effectively remove DPPH free radicals, hydroxyl radicals and superoxide anion radicals, and inhibit low density lipids. Oxidation of proteins. Chlorogenic acid plays an important role in effectively eliminating free radicals in the body, maintaining the normal structure and function of somatic cells, preventing and delaying the onset of tumor mutation and aging.

2. Antibacterial and antiviral effects

Chlorogenic acid and isochloric acid have significant inhibitory and killing effects on various pathogenic bacteria such as Staphylococcus aureus, hemolytic streptococcus, dysentery bacillus, typhoid bacillus, pneumococcal, etc., and their antibacterial mechanism and non-competitiveness Inhibition of the action of arylamine acetyltransferase (NAT). Chlorogenic acid has obvious curative effect on acute pharyngitis and skin diseases, and is clinically used for treating acute bacterial infections. According to reports in the literature, chlorogenic acid has antiviral, hemostasis, increased white blood cells, and shortened blood coagulation and bleeding time.

3. Anti-mutation, anti-tumor effect

Chlorogenic acid has a strong ability to inhibit mutation, inhibit abrupt changes induced by aflatoxin B and mutation induced by subdigestion, and can effectively reduce bone marrow red blood cell mutation caused by γ-ray. Chlorogenic acid can reduce the utilization rate of carcinogens and their transportation in the liver, and achieve anti-cancer effect. It has a significant inhibitory effect on colorectal cancer, liver cancer and laryngeal cancer and is considered to be an effective cancer chemical protectant.

4. Cardiac protection

As a free radical scavenger and antioxidant, chlorogenic acid has been extensively demonstrated that the biological activity of chlorogenic acid protects the cardiovascular system. Chlorogenic acid protects vascular endothelial cells by scavenging free radicals and anti-lipid peroxidation, and plays a role in the prevention and treatment of atherosclerosis, thromboembolic disease and hypertension.

5. Reduce the role of cholesterol

After the alcohol extract of Eucommia ulmoides was administered to rats, the serum total cholesterol was significantly lower than that of the control group, which proved that Eucommia ulmoides could inhibit the absorption of cholesterol.

6. Sex hormones and gonadotropin-like effects

Eucommia extract can increase the weight of the animal's prostate, ovary, testis, and levator ani muscles.