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Cosmetic Raw Material

Hyaluronic Acid Powder Bulk

Hyaluronic Acid Powder Bulk

Product name:Hyaluronic Acid powder
Other name: HA,Hyaluronan,Sodium Hyaluronate
CAS: 9004-61-9
Molecular Weight: 0.8~1.80 Million Daltons
Appearance:White powder
Assay: 95% min.
Standard: GB, USP, EP
Certifications: ISO, HACCP, CQC, KOSHER
Delivery: Shipped in Same day from stocks
Packing:
Carton:1-10kg
Drum: 20,25kg
Pallet:12drums/pallet,or 30cartons/pallet
Storage: Well-closed, dry place with constant 2-8℃
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Introduction:


Hyaluronic Acid Powder Bulk is a mucopolysaccharide, which widely exists in the extracellular matrix of human and vertebrate tissues and the capsule of some streptococcus, and has important physiological and pharmacological effects; the chemical structure is a linear large chain composed of a disaccharide repeating unit. Molecular polysaccharide, the chemical structure is a linear macromolecular polysaccharide composed of disaccharide repeating units, with a molecular weight of 10,000-4 million Da. Each HA molecule is composed of 30-10,000 disaccharide units.

 


COA of Hyaluronic Acid Powder Bulk:


ItemStandardTest Result
Assay95.0%~105.0%97.40%
Glucuronic acid46.0%~51.0%47.10%
Organoleptic

AppearancePowder or granulesConforms 
ColorWhite or almost whiteConforms
Physical Characteristics 

Infrared absorptionPositiveConforms
Reaction of sodium PositiveConforms
Bulk Density≥0.2g/cm³0.55g/cm³
Transparency≥99.0%99.7%
pH6.0~7.56.8
Intrinsic viscosity≤0.47dL/g0.25dL/g
Molecular weight≤10000Da4359Da
Kinematic viscosityActual value1.08mm²/s
Loss on drying≤10%4.59%
Residue on ignition≤20%18.78%
Protein≤0.05%0.04%
Heavy metals

Total Heavy Metals≤20.0ppmConforms
Arsenic(As)≤2.0ppmConforms
Microbiological Tests

Total Plate Count ≤100cfu/g<10cfu/g
Yeast & Mold≤20cfu/g<10cfu/g
E.Coli.NegativeConforms
SalmonellaNegativeConforms
StaphylococcusNegativeConforms
ConclusionConforms to the In-house standard

hyaluronic acid for skinhyaluronic acid serum

Detection:


1. Content detection

Glucuronic acid content: 42%~48%

Pure theoretical content = 194.1/401.3 = 48.37%

glucuronic acid molecular weight = 194.1

Disaccharide unit molecular weight = 401.3

HA content = glucuronic acid content x 2.0675

87 ~ 99%

2. Molecular weight detection

Numerical value of molecular weight obtained by measuring intrinsic viscosity

M.W.=[(ŋ)/3.6×10-4]1.282

3. Viscosity detection

Testing with specialized viscosity agents


Application:


1. Cosmetics

Hyaluronic Acid Powder Bulk is the ideal natural moisturizing factor added to cosmetics. It can be used in almost all cosmetics, such as creams, lotions, masks, essences, etc. It can also be used in shampoo, hair care, mousse, facial cleanser, and other products.

2. Food

It can be directly used to produce functional snacks, beverages, and so on.

3. Health products

It can be used as a raw material for health products to produce health products with special properties.

4. Medicine

The compound formed by the reaction of hyaluronic acid and other drugs exerts a sustained release effect on the drug and can achieve the purpose of directional and timed release.

It can be used as a viscoelastic agent for ophthalmic intraocular lens implantation surgery, as a filler for joint surgery such as osteoarthritis and rheumatoid arthritis, and is widely used in eye drops as a medium, and is also used to prevent postoperative adhesions and promote Healing of skin wounds.

It can promote the proliferation and migration of fibroblasts, induce the formation of blood vessels, activate macrophages, and activate lymphocytes.

hyaluronic acid before and after

Hyaluronic acid has a history of more than 60 years since it was first used in human medicine in the late 1950s. Due to its special rheological properties and physiological functions, hyaluronic acid is widely used in the field of biomedicine. So far, the design research of new hyaluronic acid derivatives has made great progress, and more and more hyaluronic acid products have been developed to fill the gap of biomedical applications.

If you want to know more information about hyaluronic acid and buy Hyaluronic Acid Powder Bulk, please contact us!

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